Reg1 Antibody [DyLight 405]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 405

Reg1 Antibody [DyLight 405] Summary

• Immunogen: E. coli-derived recombinant mouse Reg1
  Gln22-Gly165
  Accession # P43137
• Specificity: Detects mouse Reg1 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse (rm) Reg2 is observed and less than 5% cross-reactivity with rmReg3A, recombinant human (rh) Reg1B, rhReg4, recombinant rat (rr) Reg3 and rrReg2 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: Reg1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Reg1 Antibody [DyLight 405]

• ICRF
• Islet cells regeneration factor
• Islet of Langerhans regenerating protein
• lithostathine-1-alpha
• Pancreatic stone protein
• pancreatic stone protein, secretory
• Pancreatic thread protein
• protein-X
• PSPregenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic threadprotein)
• PSPS1REG-1-alpha
• PSPSMGC12447
• PTPP19
• Reg1
• regenerating islet-derived 1 alpha
• Regenerating islet-derived protein 1-alpha
• Regenerating protein I alpha
• REGlithostathine 1 alpha

Background

REG1, also known as Lithostathine-1-alpha, is a secreted 19kDa 166 amino acid protein. The gene is a type I subclass member of the Reg gene family and is associated with pancreas and brain regeneration. Current research on REG1 is being conducted in relation to cystic fibrosis, nephropathy, cerebral atherosclerosis, hereditary pancreatitis, pancreatitis, celiac disease, hepatocellular carcinoma, Alzheimer's disease and Down syndrome. REG1 has been linked to the secretion, cell proliferation, coagulation and cell growth pathways where it interacts with REG3A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: Reg1