Rae-1 Antibody (186107) [Fluorescein] - Pan Specific

RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse Rae-1 Pan Specific Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB17582F, filled histogram) or isotype control antibody (Catalog # IC006F, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Mu
• Applications: Flow
• Clone: 186107
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Fluorescein

Rae-1 Antibody (186107) [Fluorescein] - Pan Specific Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Rae-1δ
  Leu29-Ser227
  Accession # Q9JI58
• Specificity: Detects mouse Rae‑1. It recognizes Rae-1 alpha , beta , δ, gamma and epsilon .
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: Raet1a
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rae-1 Antibody (186107) [Fluorescein] - Pan Specific

• dJ481F12.3;dJ800J21.1;Gle2;MIG14;Mnrp41;mRNA export factor RAE1;MRNP41;RAE1
• Rae1
• Rae-1

Background

Rae-1 alpha , beta , gamma , δ and epsilon comprise a family of closely related (88-95% amino acid identity) GPI-linked cell surface proteins that function as ligands for mouse NKG2D, an activating receptor expressed on NK and T cells. Rae-1 transcripts are expressed in mouse embryos and several tumor cell lines but are absent from most normal adult tissues. Rae-1 protein expression on tumor cell lines has been implicated in in vivo tumor rejection.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Rae-1 Antibody (FAB17582F)(3)

Publications using FAB17582F

• Li Z, Zhang C, Zhou Z, Zhang J, Zhang J, Tian Z Small intestinal intraepithelial lymphocytes expressing CD8 and T cell receptor gammadelta are involved in bacterial clearance during Salmonella enterica serovar Typhimurium infection. Infect. Immun., 2011-12-05;80(2):565-74. 2011-12-05 [PMID: 22144492] (Flow Cytometry, Mouse)
• Carayannopoulos LN, Barks JL, Yokoyama WM Murine trophoblast cells induce NK cell interferon-gamma production through KLRK1. Biol. Reprod., 2010-05-19;83(3):404-14. 2010-05-19 [PMID: 20484740] (Flow Cytometry, Mouse)
• Kong LY, Gelbard A, Wei J Inhibition of p-STAT3 enhances IFN-alpha efficacy against metastatic melanoma in a murine model. Clin. Cancer Res., 2010-04-13;16(9):2550-61. 2010-04-13 [PMID: 20388845] (Flow Cytometry, Mouse)

Bioinformatics

• Gene Symbol: Raet1a
• Uniprot:
  • Q9JI58()