Rad51D Antibody (Rad51D 5B3/6) [DyLight 405]

Product Discontinued

Rad51D Antibody (Rad51D 5B3/6) [DyLight 405] Summary

• Immunogen: His-tagged human Rad51D, overexpressed in e.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page
• Specificity: Detects as little as 10ng of purified protein. Dilutions Western Blot 1:1000Immunocytochemistry/Immunofluorescence 1:100-1:500
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RAD51D
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Rad51D Antibody (Rad51D 5B3/6) [DyLight 405]

• DNA repair protein RAD51 homolog 4
• HsTRAD
• R51H3Trad
• RAD51 homolog D
• RAD51DRAD51 (S. cerevisiae)-like 3
• RAD51-like 3 (S. cerevisiae)
• RAD51-like protein 3
• recombination repair protein
• TRAD

Background

The Rad51 DNA repair protein is a key component of the double-strand break repair pathway and is essential for mitotic and meiotic recombination and genomic stability. Five human RAD51 homologues have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologues interacts with one or more of the others, with all of the proteins involved with either one complex or with multiple smaller complexes. RAD51D interacts with XRCC2 and RAD51C (1). RAD51D's expression pattern and sequence similarity to other RAD51 family members most likely makes it part of a complex of proteins required for DNA repair and meiotic recombination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAD51D