RAB37 Antibody (OTI2F1)

Western Blot: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RAB37.

Immunohistochemistry: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of Human Kidney tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunohistochemistry: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of Human endometrium tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunohistochemistry: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunohistochemistry: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunohistochemistry: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of Human prostate tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunohistochemistry: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of Human breast tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunohistochemistry: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of Human pancreas tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunohistochemistry: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of Human lymphoma tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunofluorescence: RAB37 Antibody (OTI2F1) [NBP2-45926] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY RAB37.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IHC
• Clone: OTI2F1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

RAB37 Antibody (OTI2F1) Summary

• Immunogen: Full length human recombinant protein of human RAB37(NP_783865) prduced in HEK293T cell.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: RAB37
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150
  • Western Blot 1:2000
• Theoretical MW: 24 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for RAB37 Antibody (OTI2F1)

• FLJ32507
• member of RAS oncogene family
• RAB37, member RAS oncogene family
• ras-related protein Rab-37

Background

Belonging to the small GTPase superfamily/ Rab family, RAB37 is involved with protein transport and small GTPase mediated signal transduction. Being a critical regulator of vesicular fusion and trafficking, Rab proteins are low molecular mass GTPases. Similarly, the molecular functions of these proteins include protein and GTP binding. RAB37 interacts with RAB5A, RIMS1, EWSR1, DTX4 and PCSK5. Diseases associated with RAB37 include renal cell carcinoma, lung cancer, hemophagocytic lymphohistiocytosis, Crohn's disease, psoriasis and neuronitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAB37