PTPN12 Antibody [FITC]

• Reactivity: Hu
• Applications: ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: FITC

PTPN12 Antibody [FITC] Summary

• Immunogen: Produced in rabbits immunized with purified, recombinant Human PTPN12 (Accession#: AAA36529.1; Met1-Gln355)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTPN12
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Alternate Names for PTPN12 Antibody [FITC]

• protein tyrosine phosphatase, non-receptor type 12
• Protein-tyrosine phosphatase G1
• PTPG1
• PTPG1tyrosine-protein phosphatase non-receptor type 12
• PTPN12
• PTP-PEST
• PTP-PESTEC 3.1.3.48

Background

PTPN12 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may be related to protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of oncogene c-ABL, thus may play a role in oncogenesis. This PTP was shown to interact with, and dephosphorylate, various of cytoskeleton and cell adhesion molecules, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin, which suggested its regulatory roles in controlling cell shape and mobility.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPN12