PTPN12 Products

Antibodies
PTPN12 Antibody
PTPN12 Antibody
NBP1-87188
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PTPN12 Antibody
PTPN12 Antibody
NBP2-20004
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PTPN12 Antibody
PTPN12 Antibody
NB100-60666
Species: Hu, Mu
Applications: WB, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
PTPN12 Overexpression Lysate ...
PTPN12 Overexpression Lysate (Dena...
H00005782-T01
Species: Hu
Applications: WB
PTPN12 Overexpression Lysate ...
PTPN12 Overexpression Lysate (Native)
NBL1-14969
Applications: WB
Proteins
PTPN12 Recombinant Protein An ...
PTPN12 Recombinant Protein Antigen
NBP1-87188PEP
Species: Hu
Applications: AC
Recombinant Human PTPN12 Prot ...
Recombinant Human PTPN12 Protein
H00005782-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human PTPN12 Prot ...
Recombinant Human PTPN12 Protein
H00005782-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
PTPN12 RNAi
PTPN12 RNAi
H00005782-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PTPN12 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may be related to protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of oncogene c-ABL, thus may play a role in oncogenesis. This PTP was shown to interact with, and dephosphorylate, various of cytoskeleton and cell adhesion molecules, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin, which suggested its regulatory roles in controlling cell shape and mobility.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 5782
Alternate Names
  • Protein-tyrosine phosphatase G1
  • PTP-PESTEC 3.1.3.48
  • PTPG1tyrosine-protein phosphatase non-receptor type 12
  • protein tyrosine phosphatase, non-receptor type 12

PTMs for PTPN12

Learn more about PTMs related to PTPN12.

Phosphorylation
Dephosphorylation
Cleavage
Reduction
Methylation

Bioinformatics Tool for PTPN12

Discover related pathways, diseases and genes to PTPN12. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.