PTK7/CCK4 Antibody (4F9)

Western Blot: PTK7/CCK4 Antibody (4F9) [NBP1-51633] - Analysis using PTK7 mouse mAb against Hela (1), A431 (2), HCT116 (3), Caco2 (4), HepG2 (5) and MCF-7 (6) cell lysate.

Immunohistochemistry-Paraffin: PTK7/CCK4 Antibody (4F9) [NBP1-51633] - Analysis of lung cancer tissues using PTK7 mouse mAb with DAB staining.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clone: 4F9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

PTK7/CCK4 Antibody (4F9) Summary

• Immunogen: Purified recombinant fragment of human PTK7/CCK4 expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTK7
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:1000
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 118 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.03% Sodium Azide
• Purity: Unpurified

Alternate Names for PTK7/CCK4 Antibody (4F9)

• CCK4
• CCK-4
• CCK4Colon carcinoma kinase 4
• colon carcinoma kinase-4
• Protein-tyrosine kinase 7
• Pseudo tyrosine kinase receptor 7
• PTK7 protein tyrosine kinase 7
• PTK7
• Tyrosine-protein kinase-like 7

Background

Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTK7
• Entrez:
  • 5754(Human)
• Uniprot:
  • Q13308()