PTGER4/EP4 Antibody

Western Blot: PTGER4/EP4 Antibody [H00005734-D01P] - Analysis of PTGER4 expression in Jurkat.

Western Blot: PTGER4/EP4 Antibody [H00005734-D01P] - Analysis of PTGER4 expression in transfected 293T cell line by PTGER4 polyclonal antibody.Lane 1: PTGER4 transfected lysate(53.10 KDa).Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

PTGER4/EP4 Antibody Summary

• Immunogen: PTGER4 (NP_000949.1, 1 a.a. - 488 a.a.) full-length human protein. MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
• Specificity: Reacts with prostaglandin E receptor 4 (subtype EP4).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTGER4
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against cell and transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PTGER4/EP4 Antibody

• EP4
• EP4R
• MGC126583
• PGE receptor EP4 subtype
• PGE receptor, EP4 subtype
• PGE2 receptor EP4 subtype
• prostaglandin E receptor 4 (subtype EP4)
• prostaglandin E2 receptor EP4 subtype
• Prostanoid EP4 receptor
• PTGER2
• PTGER4

Background

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PTGER4/EP4 Antibody (H00005734-D01P)(1)

Publication using H00005734-D01P

• Xiao J, Li Y, Jones-Brando L et al. Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains. J Neural Transm 2013-07-03 [PMID: 23821371]

Bioinformatics

• Gene Symbol: PTGER4
• Entrez:
  • 5734(Human)
• Uniprot:
  • NP_000949.1(Human)