PSMG1 Antibody (4F2) - Azide and BSA Free

Sandwich ELISA: PSMG1 Antibody (4F2) [H00008624-M01] - Detection limit for recombinant GST tagged DSCR2 is approximately 0.03ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 4F2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

PSMG1 Antibody (4F2) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: DSCR2 (AAH03619, 1 a.a. ~ 288 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAATFFGEVVKAPCRAGTEDEEEEEEGRRETPEDREVRLQLARKREVRLLRRQTKTSLEVSLLEKYPCSKFIIAIGNNAVAFLSSFVMNSGVWEEVGCAKLWNEWCRTTDTTHLSSTEAFCVFYHLKSNPSVFLCQCSCYVAEDQQYQWLEKVFGSCPRKNMQITILTCRHVTDYKTSESTGSLPSPFLRALKTQNFKDSACCPLLEQPNIVHDLPAAVLSYCQVWKIPAILYLCYTDVMKLDLITVEAFKPILSTRSLKGLVKNIPQSTEILKKLMTTNEIQSNIYT
• Specificity: DSCR2 - Down syndrome critical region gene 2
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PSMG1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot
• Application Notes: Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PSMG1 Antibody (4F2) - Azide and BSA Free

• C21-LRP
• C21LRPc21-LRP
• Chromosome 21 leucine-rich protein
• Down syndrome critical region gene 2
• DSCR2leucine rich protein C21-LRP
• LRPC21
• PAC-1
• PAC1Down syndrome critical region protein 2
• proteasome (prosome, macropain) assembly chaperone 1
• proteasome assembling chaperone 1
• proteasome assembly chaperone 1

Background

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PSMG1 Antibody (H00008624-M01)(2)

Publications using H00008624-M01

• Dasuri K, Zhang L, Ebenezer P et al. Aging and dietary restriction alter proteasome biogenesis and composition in the brain and liver. Mech Ageing Dev. 2009-11-06 [PMID: 19896962]
• Song HJ, Park J, Seo SR et al. Down syndrome critical region 2 protein inhibits the transcriptional activity of peroxisome proliferator-activated receptor beta in HEK293 cells. Biochem Biophys Res Commun;376(3):478-82. 2008-11-21 [PMID: 18793612]

Bioinformatics

• Gene Symbol: PSMG1
• Entrez:
  • 8624(Human)
• OMIM:
  • 605296(Human)
• Uniprot:
  • AAH03619(Human)