Proprotein Convertase 2/PCSK2 Antibody

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Western Blot: Proprotein Convertase 2/PCSK2 Antibody [H00005126-D01P] - Analysis of PCSK2 expression in mouse liver.
Western Blot: Proprotein Convertase 2/PCSK2 Antibody [H00005126-D01P] - Analysis of PCSK2 expression in human liver.
Western Blot: Proprotein Convertase 2/PCSK2 Antibody [H00005126-D01P] - Analysis of PCSK2 expression in transfected 293T cell line by PCSK2 polyclonal antibody.Lane 1: PCSK2 transfected lysate(70.60 KDa).Lane 2: ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Proprotein Convertase 2/PCSK2 Antibody Summary

Immunogen
PCSK2 (NP_002585.2, 1 a.a. - 638 a.a.) full-length human protein. MKGGCVSQWKAAAGFLFCVMVFASAERPVFTNHFLVELHKGGEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELDEAVERSLKSILNKN
Specificity
PCSK2 - proprotein convertase subtilisin/kexin type 2,
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PCSK2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Proprotein Convertase 2/PCSK2 Antibody

  • EC 3.4.21
  • EC 3.4.21.94
  • KEX2-like endoprotease 2
  • NEC 2
  • NEC2
  • NEC2SPC2
  • neuroendocrine convertase 2
  • PC2
  • PC2NEC-2
  • PCSK2
  • Prohormone convertase 2
  • Proprotein Convertase 2
  • proprotein convertase subtilisin/kexin type 2
  • SPC2

Background

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PCSK2
Entrez
Uniprot