Prodynorphin/PDYN Antibody - BSA Free

Western Blot: Prodynorphin/PDYN Antibody [NBP1-91500] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

Prodynorphin/PDYN Antibody - BSA Free Summary

• Description: The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
• Immunogen: Synthetic peptide directed towards the middle region of human Prodynorphin/PDYN. Peptide sequence TLTVSGLRGKDDLEDEVALEEGYSALAKLLEPVLKELEKSRLLTSVPEEK. The peptide sequence for this immunogen was taken from within the described region.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDYN
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1.0 ug/ml
• Theoretical MW: 28 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, 2% Sucrose
• Preservative: 0.09% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Affinity purified

Alternate Names for Prodynorphin/PDYN Antibody - BSA Free

• ADCA
• Beta-neoendorphin-dynorphin
• leu-enkephalin
• leumorphin
• neoendorphin-dynorphin-enkephalin prepropeptide
• PENKB
• preprodynorphin
• preproenkephalin B
• proenkephalin-B
• rimorphin
• SCA23

Background

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Prodynorphin/PDYN Antibody (NBP1-91500)(1)

Publication using NBP1-91500

• Jiang QY, Wang MY, Li L et al. Electroacupuncture relieves labour pain and influences the spinal dynorphin/?-opioid receptor system in rats. Acupunct Med 2016-01-05 [PMID: 26732307]

Bioinformatics

• Gene Symbol: PDYN
• Uniprot:
  • NP_061351(Mouse)
  • O35417(Mouse)