PPAP2C Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

PPAP2C Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human PPAP2C
  
  

  Source: E.coli

  Amino Acid Sequence: PYKRGFYCGDDSIRYPYRPDTIT

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: PLPP2
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10-100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP3-25062It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for PPAP2C Recombinant Protein Antigen

• EC 3.1.3.4
• LPP2PAP2-g
• PAP2c
• PAP-2clipid phosphate phosphohydrolase 2
• PAP2-G
• PAP2-gamma
• Phosphatidate phosphohydrolase type 2c
• Phosphatidic acid phosphatase 2c
• phosphatidic acid phosphatase type 2C
• phosphatidic acid phosphohydrolase type 2c
• type-2 phosphatidic acid phosphatase-gamma

Background

PPAP2C, also referred to as Phosphatidic Acid Phosphatase Type 2C, has a canonical sequence that is 288 amino acids long and approximately 32kDa, and two other isoforms that are 309 and 232 amino acids in length, respectively. PPAP2C is an enzyme that hydrolyzes S1P, C1P and LPA, and catalyzes the conversion of phosphatidic acid to diacylglycerol. Current research surrounding PPAP2C has shown a possible linkage with strabismus and gastroenteritis. PPAP2C has also been shown to interact with APLP1, BAG6, GALC, MLH1, and UNC119 in pathways such as triacylglyceride synthesis, sphingolipid metabolism, triacylglycerol biosynthesis, and Fc gamma R-mediated phagocytosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLPP2