POU3F3 Antibody

Product Discontinued

POU3F3 Antibody Summary

• Immunogen: POU3F3 (NP_006227, 401 a.a. ~ 501 a.a) partial recombinant protein with GST tag.AAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHHGLQTSVQ
• Specificity: POU3F3 - POU domain, class 3, transcription factor 3
• Clonality: Polyclonal
• Host: Mouse
• Gene: POU3F3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Unpurified antisera so the specific antibody concentration is unknown. Contains 50% glycerol.
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for POU3F3 Antibody

• brain-1
• Brain-specific homeobox/POU domain protein 1
• Brn-1
• BRN1brn-1
• Oct-8
• Octamer-binding protein 8
• Octamer-binding transcription factor 8
• OTF-8
• OTF8oct-8
• POU class 3 homeobox 3
• POU domain class 3, transcription factor 3
• POU domain, class 3, transcription factor 3

Background

POU3F3 is a member of the class III POU family of transcription factors (see POU3F1; MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for POU3F3 Antibody (H00005455-A01)(1)

Publication using H00005455-A01

• Weimer JM, Yokota Y, Stanco A et al. MARCKS modulates radial progenitor placement, proliferation organization in the developing cerebral cortex. Development;136(17):2965-2975. 2009-01-01 [PMID: 19666823]

Bioinformatics

• Gene Symbol: POU3F3
• Entrez:
  • 5455(Human)
• OMIM:
  • 602480(Human)
• Uniprot:
  • NP_006227(Human)