Polypeptide GalNac Transferase 1/GALNT1 Antibody [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Janelia Fluor 646

Polypeptide GalNac Transferase 1/GALNT1 Antibody [Janelia Fluor® 646] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Polypeptide GalNac Transferase 1/GALNT1
  Gly41-Phe559
  Accession # Q10472
• Specificity: Detects human Polypeptide GalNac Transferase 1/GALNT1 in direct ELISAs and Western blots. In direct ELISAs, less than
  5% cross‑reactivity with recombinant human (rh) GALNT2 and rhGALNT3 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: GALNT1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Polypeptide GalNac Transferase 1/GALNT1 Antibody [Janelia Fluor® 646]

• EC 2.4.1.41
• GalNAc transferase 1
• GALNAC-T1
• GALNT1
• Polypeptide GalNAc transferase 1
• polypeptide N-acetylgalactosaminyltransferase 1
• pp-GaNTase 1
• Protein-UDP acetylgalactosaminyltransferase 1
• UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1
• UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 1 (GalNAc-T1)

Background

GALNT1 encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GALNT1