Recombinant Human PLUNC His Protein

SDS-Page: Recombinant Human PLUNC Protein [NBP2-22716]

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human PLUNC His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 20-256 of Human PLUNC
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSQFGGLPV PLDQTLPLNV NPALPLSPTG LAGSLTNALS NGLLSGGLLG ILENLPLLDI LKPGGGTSGG LLGGLLGKVT SVIPGLNNII DIKVTDPQLL ELGLVQSPDG HRLYVTIPLG IKLQVNTPLV GASLLRLAVK LDITAEILAV RDKQERIHLV LGDCTHSPGS LQISLLDGLG PLPIQGLLDS LTGILNKVLP ELVQGNVCPL VNEVLRGLDI TLVHDIVNML IHGLQFVIKV

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: BPIFA1
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 27.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 0.2 M NaCl, 30% glycerol
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human PLUNC His Protein

• bA49G10.5
• BPIFA1
• ligand-binding protein RYA3
• LPLUNC3
• Lung-specific protein X
• LUNX
• LUNXNASG
• Nasopharyngeal carcinoma-related protein
• Palate lung and nasal epithelium clone protein
• palate, lung and nasal epithelium associated
• palate, lung and nasal epithelium carcinoma associated
• PLUNC
• protein Plunc
• Secretory protein in upper respiratory tracts
• SPLUNC1
• SPLUNC1SPURT
• tracheal epithelium enriched protein
• Tracheal epithelium-enriched protein
• Von Ebner protein Hl

Background

BPIFA1, also known as PLUNC, belongs to the short subfamily of PLUNC family proteins and have homology only to the Nterminal domains of BPI. It is a secreted protein that is expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. BPIFA1 binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of BPIFA1 occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of BPIFA1 in the upper respiratory tract. Recombinant human BPIFA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: BPIFA1