Plexin B1 Antibody [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 488

Plexin B1 Antibody [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human Plexin B1
  Leu35-Val150
  Accession # O43157
• Specificity: Detects human Plexin B1 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human Plexin B3 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Plexin B1 Antibody [Alexa Fluor® 488]

• Plexin B1
• PLXN5
• PLXNB1
• SEP
• Transmembrane Protein SEP

Background

Plexin B1 is a type I transmembrane protein that belongs to the Plexin family of semaphorin receptors. It is derived from a single peptide that undergoes proteolytic processing in its extracellular domain to form the non-covalently-linked heterodimer of the extracellular alpha subunit and the transmembrane beta subunit. Human Plexin B1 extracellular alpha subunit shares homology with semaphorins, HGF receptor and MSP receptor and contains a sema domain and three IPT/TIG domains. It functions as a receptor for semaphorin 4D/CD100. Multiple splice isoforms of Plexin B1 have been reported. Within the region used as immunogen, human Plexin B1 shares 90% and 97% amino acid sequence homology with mouse and canine Plexin B1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.