PLC-beta 1 Antibody [HRP]

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: HRP

PLC-beta 1 Antibody [HRP] Summary

• Immunogen: E. coli-derived recombinant human PLC-beta 1
  Lys27-Met245
  Accession # Q9NQ66
• Specificity: Detects human and mouse PLC-beta 1, but does not detect recombinant human (rh) PLC-beta 2, rhPLC-beta 3, or rhPLC-beta 4 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: PLCB1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Alternate Names for PLC-beta 1 Antibody [HRP]

• EC 3.1.4.11
• EIEE12
• FLJ45792
• inositoltrisphosphohydrolase
• KIAA05811-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1
• monophosphatidylinositol phosphodiesterase
• phosphoinositidase C
• Phosphoinositide phospholipase C-beta-1
• phospholipase C, beta 1 (phosphoinositide-specific)
• Phospholipase C-beta-1
• Phospholipase C-I
• PI-PLC
• PLC-154
• PLC154,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
• PLCB1
• PLCB1A
• PLCB1B
• PLCbeta 1
• PLC-beta 1
• PLC-beta-1
• PLC-I
• PLC-I1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
• triphosphoinositide phosphodiesterase

Background

Phospholipase C beta 1 is encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLCB1