PLA2G3 Antibody - BSA Free

Immunohistochemistry-Paraffin: PLA2G3 Antibody - BSA Free [NB100-59031] - Brain, Glioblastoma

Immunohistochemistry-Paraffin: PLA2G3 Antibody - BSA Free [NB100-59031] - Analysis of anti-PLA2G3 antibody with human colon carcinoma at concentration 5 ug/ml.

Immunohistochemistry-Paraffin: PLA2G3 Antibody - BSA Free [NB100-59031] - Brain, Hypothalamus, neurons

• Reactivity: Hu, Po, Bv, Pm, Pm, Mu, Eq
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

PLA2G3 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 12 amino acid peptide from internal region of human PLA2G3.
• Epitope: internal domain of human
• Localization: Secreted
• Specificity: Human PLA2G3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (92%), Equine (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLA2G3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2.5 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Bat (83%), Canine (83%), Opossum (83%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PLA2G3 Antibody - BSA Free

• EC 3.1.1.4
• GIII SPLA2
• GIII-SPLA2
• group 3 secretory phospholipase A2
• group III secreted phospholipase A2
• Group III secretory phospholipase A2
• Phosphatidylcholine 2-acylhydrolase 3
• phosphatidylcholine 2-acylhydrolase GIII
• phospholipase A2, group III
• PLA2G3
• SPLA2III
• SPLA2-III

Background

PLA2G3 (Human group III secreted phospholipase A2) belongs to a superfamily of intracellular and secreted enzymes that catalyze the hydrolysis of glycerophospholipids to release fatty acids and lysophospholipids. Human PLA2G3 has been shown to be a calcium dependent enzyme, consisting of a central group III sPLA2 domain flanked by unique N and C terminal domains that are proteolytically cleavedin most tissues. The sPLA2 domain is sufficient for catalytic activity. SPLA2-III is expressed in the microvascular endothelium of tissues with inflammation, ischemic injury and cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLA2G3
• Entrez:
  • 50487(Human)