PKHD1 Antibody [DyLight 405]

Product Discontinued

PKHD1 Antibody [DyLight 405] Summary

• Immunogen: A synthetic peptide derived from the human PKHD1 protein (within residues 100-200). [UniProt# Q8TCZ9]
• Localization: Membrane; single-pass type I membrane.
• Predicted Species: Mouse (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PKHD1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human. Immunogen displays the following percentage of sequence identity for non-tested species: mouse (93%).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PKHD1 Antibody [DyLight 405]

• polycystic kidney and hepatic disease 1 (autosomal recessive)

Background

Found mainly in the cytoplasm and plasma membrane, PKHD1 plays an important role in protein binding and receptor activity. The protein encoded by PKHD1 has a single transmembrane (TM) spanning domain and various copies of an immunoglobulin-like plexin-transcription-factor domain. More specifically, these transcripts encode products which lack the TM and may be secreted. In humans, PKHD1 is highly expressed in the kidney by acting as a receptor protein in the cortical and medullary collecting ducts. Diseases associated with PKHD1 include polycystic kidney and hepatic disease, liver disease, neoplasia, fibrosis, cancer, adenocarcinoma and prostate cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PKHD1