PKA R2 Antibody (H2 006 D4)

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Western Blot: PKA R2 Antibody (H2 006 D4) [NB100-74498] - Analysis of PKA RII in human saliva.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
H2 006 D4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

PKA R2 Antibody (H2 006 D4) Summary

Immunogen
Column purified fraction of cAMP dependent PKA RII from human saliva.
Localization
Cytoplasmic and Plasma membrane
Specificity
PKA RII (H2 006 D4)
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PRKAR2A
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Application Notes
Useful in WB. WB: Detects an approx. 50 kDa protein representing PKA RII in human saliva.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for PKA R2 Antibody (H2 006 D4)

  • protein kinase, cAMP-dependent, regulatory, type II, alpha
  • RII-alpha subunit

Background

The type 1(RI) and type 2 (RII) subunit of cyclic AMP-dependent protein kinase A (PKA) is a polyfunctional protein that is present in most tissues and cells. The many roles of RII include: 1) the regulation of extracellular cyclic AMP levels, 2) catalyzing the phosphorylation of the transcription factor CREB, 3) aiding in the development of mammalian oocytes and 4) phosphorylation of proteins to enhance the release of neurotransmitters. Localization of PKA is coordinated through association with A-kinase anchoring proteins (AKAPs) that bind to a 14-18aa sequence in subunit RII.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PRKAR2A
Entrez