PIEZO1 Antibody

Immunohistochemistry-Paraffin: PIEZO1 Antibody [NBP2-13758] - Staining in human lung and skeletal muscle tissues . Corresponding PIEZO1 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: PIEZO1 Antibody [NBP2-13758] - Staining of human skeletal muscle shows no cytoplasmic positivity in myocytes as expected.

Immunohistochemistry-Paraffin: PIEZO1 Antibody [NBP2-13758] - Staining of human lung shows positivity in erythrocytes.

Immunohistochemistry-Paraffin: PIEZO1 Antibody [NBP2-13758] - Staining of human lung shows moderate positivity in pneumocytes.

Immunohistochemistry-Paraffin: PIEZO1 Antibody [NBP2-13758] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuropil.

Product Discontinued

PIEZO1 Antibody Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to the amino acids: SVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIIPFTAQAYEELSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKH
• Predicted Species: Mouse (95%), Rat (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PIEZO1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PIEZO1 Antibody

• FAM38A
• KIAA0233
• member A
• membrane protein induced by beta-amyloid treatment
• Mib
• PIEZO1
• piezo-type mechanosensitive ion channel component 1
• Protein FAM38A

Background

PIEZO1 (piezo-type mechanosensitive ion channel component 1) plays a crucial role in epithelial cell adhesion. PIEZO1 belongs to the PIEZO family of transmembrane proteins. Mutations in Piezo1 have been tied to Xerocytosis. PIEZO1 has been studied in relation to neuronitis, Alzheimer's disease and Parkinson's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIEZO1