Phosphorylase B Native Protein

• Reactivity: Rb
• Applications: ELISA
• Concentration: 5 mg/ml

Phosphorylase B Native Protein Summary

• Description: Native rabbit phosphorylase B.
  
  

  Source:Rabbit skeletal muscle

• Protein/Peptide Type: Native Protein
• Gene: PHKB
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • ELISA
• Theoretical MW: 185 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Preservative: No Preservative
• Concentration: 5 mg/ml
• Purity: >95%
• Reconstitution Instructions: Reconstitute in sterile distilled water.

Alternate Names for Phosphorylase B Native Protein

• DKFZp781E15103
• FLJ41698
• phosphorylase b kinase regulatory subunit beta
• phosphorylase kinase beta-subunit
• Phosphorylase kinase subunit beta
• phosphorylase kinase, beta

Background

Phosphorylase B, also known by its gene name, PHKB, is an enzyme localized to the plasma membrane that catalyzes the phosphorylation of the amino acid residue Serine. Phosphorylase B has a 1,093 amino acid long isoform that is 125 kDa (the canonical sequence) and three other isoforms derived from alternative splicing. Current research on PHKB is being performed relating to several diseases and disorders including hepatitis and metabolic disorders, such as hypoglycemia and glycogen storage disease. Phosphorylase B has also been shown to have interactions with B Raf, hnRNP C1 + C2, PASK, and UBE3A in pathways such as Glucose and Glycogen Metabolism, PKA Signaling, cAMP Pathway, Insulin Signaling Pathway and Calcium Signaling Pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: PHKB