Human Peroxiredoxin 3 ELISA Kit (Colorimetric)

ELISA: Peroxiredoxin 3 ELISA Kit [HRP] [KA0531] - Native human Prx3 from HeLa cell lysate was serially diluted in Standard/Sample dilution buffer. The optical density of each dilution was plotted against the ecombinant human Prx3 standard curve.

Product Discontinued

Human Peroxiredoxin 3 ELISA Kit (Colorimetric) Summary

• Description: Quality control test: Standard curve. PRDX3 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human PRDX3.
• Standard Curve Range: 2 to 32 ng/mL
• Sensitivity: <32 ng/mL
• Assay Type: Sandwich ELISA
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: PRDX3

Applications/Dilutions

• Dilutions:
  • ELISA
  • Quantification
• Application Notes: Useful for quantification.

Packaging, Storage & Formulations

• Storage: Store at 4C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human Peroxiredoxin 3 ELISA Kit (Colorimetric)

• Antioxidant protein 1MGC104387
• AOP-1
• AOP-1MGC24293
• AOP1PRO1748
• EC 1.11.1.15
• HBC189
• MER5
• Peroxiredoxin 3
• Peroxiredoxin III
• peroxiredoxin-3
• PRDX3
• Protein MER5 homolog
• Prx-III
• SP-22
• thioredoxin-dependent peroxide reductase, mitochondrial

Background

The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Peroxiredoxin 3 ELISA Kit (KA0531)(3)

Publications using KA0531

• Chang TS, Cho CS, Park S et al. Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria. J Biol Chem. 2004-10-01 [PMID: 15280382]
• Fujii J, Ikeda Y. Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein. Redox Rep. 2002-01-01 [PMID: 12189041]
• Rhee SG, Kang SW, Chang TS et al. Peroxiredoxin, a novel family of peroxidases. IUBMB Life. 2001-07-01 [PMID: 11795591]

FAQs for Peroxiredoxin 3 ELISA Kit (KA0531). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: PRDX3