Peroxiredoxin 3 Antibody

Western Blot: Peroxiredoxin 3 Antibody [H00010935-B01P] - Analysis of PRDX3 expression in human kidney.

Immunocytochemistry/Immunofluorescence: Peroxiredoxin 3 Antibody [H00010935-B01P] - Analysis of purified antibody to PRDX3 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: Peroxiredoxin 3 Antibody [H00010935-B01P] - Analysis of PRDX3 expression in A-549.

Western Blot: Peroxiredoxin 3 Antibody [H00010935-B01P] - Analysis of PRDX3 expression in A-431.

Western Blot: Peroxiredoxin 3 Antibody [H00010935-B01P] - Analysis of PRDX3 expression in transfected 293T cell line by PRDX3 polyclonal antibody. Lane 1: PRDX3 transfected lysate(28.16 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

Peroxiredoxin 3 Antibody Summary

• Immunogen: PRDX3 (NP_006784.1, 1 a.a. - 256 a.a.) full-length human protein. MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: PRDX3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional, Immunofluorescence

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Peroxiredoxin 3 Antibody

• Antioxidant protein 1MGC104387
• AOP-1
• AOP-1MGC24293
• AOP1PRO1748
• EC 1.11.1.15
• HBC189
• MER5
• Peroxiredoxin 3
• Peroxiredoxin III
• peroxiredoxin-3
• PRDX3
• Protein MER5 homolog
• prx-III
• SP-22
• thioredoxin-dependent peroxide reductase, mitochondrial

Background

The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PRDX3
• Uniprot:
  • NP_006784.1(Human)