PDZD2/PDZK3 Antibody (787924) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clone: 787924
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

PDZD2/PDZK3 Antibody (787924) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human PDZD2
  Ser2489-Ser2839
  Accession # O15018
• Specificity: Detects human PDZD2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse PDZD2 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PDZD2/PDZK3 Antibody (787924) [Alexa Fluor® 750]

• Activated in prostate cancer protein
• AIPC
• AIPCPAPIN
• KIAA0300
• KIAA0300PDZ domain-containing protein 3
• Papin
• PDZ domain containing 2
• PDZ domain containing 3
• PDZ domain-containing protein 2
• PDZD2
• PDZK3
• Pin1

Background

PDZD2 (PSD95, Discs-large and ZO-1 domain-containing protein 2), also called AIPC (activated in prostate cancer) and PDZK3, is a multi-PDZ-domain protein that is ubiquitously expressed. The 2839 amino acid (aa) human PDZD2 is found in the endoplasmic reticulum. Caspase cleavage produces the 347 aa, 37 kDa secreted mature form (aa 2493-2839). A 2640 aa isoform is lacking 199 aa N-terminal to the mature sequence. The processed, mature form contains two PDZ domains which interact with the C-terminus of partner proteins, promotes maturation of pancreatic b cells, and is highly expressed in human prostate tumors. Human PDZD2 shares 72% aa sequence identity with mouse or rat PDZD2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.