PDE3B Antibody (SMCP3B)

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Western Blot: PDE3B Antibody (SMCP3B) [NBP1-43333] - Lysates prepared from mouse heart (lane 1) or lymph node cells (lane 2) were run under reducing conditions on a 3-8% Tris-Acetate gel. The membrane was probed with 2 ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
SMCP3B
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

PDE3B Antibody (SMCP3B) Summary

Immunogen
The immunogen for this antibody was PDE3B.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
PDE3B
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This SMCP3B antibody has been tested by immunoblotting of mouse lymph node cells and mouse heart under reducing conditions. It can be used at 1-5 ug/mL.

Reactivity Notes

This antibody is reactive to Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous, may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for PDE3B Antibody (SMCP3B)

  • CGIP1
  • CGI-PDE B
  • cGIPDE1
  • cGMP-inhibited 3'-5'-cyclic phosphodiesterase B
  • Cyclic GMP-inhibited phosphodiesterase B
  • cyclic nucleotide phosphodiesterase
  • EC 3.1.4
  • EC 3.1.4.17
  • HcGIP1
  • phosphodiesterase 3B, cGMP-inhibited

Background

Cyclic nucleotide phosphodiesterases (PDE) catalyze the hydrolysis of cAMP and cGMP thereby regulating the effects of these second messengers. There are several families of PDE which share common structural organization. The PDE3 family has two members, 3A and 3B that are products of two separate genes. PDE3B (~130 kDa) is expressed predominantly in adipose tissue and lymphocytes, while PDE3A (~120 kDa) is expressed predominantly in platelets and heart tissue. The monoclonal antibody SMCP3B reacts with mouse PDE3B. The SMCP3B antibody was generated against amino acids 643-1100 in the C-terminus and does not cross-react with mouse PDE3A, as determined by western blot analysis of lysates of mouse heart tissue. The SMCP3B antibody does not cross-react with human PDE3B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PDE3B