PAC1R Antibody - BSA Free Summary
Immunogen |
Synthetic 17 amino acid peptide from C-terminus of human PAC1R. |
Epitope |
C-Terminus |
Localization |
Cell Membrane |
Specificity |
Human ADCYAP1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Predicted Species |
Fish (94%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
ADCYAP1R1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin 15 ug/ml
|
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Mouse (88%), Rat (88%), Hamster (88%), Bovine (88%), Equine (88%), Porcine (88%).
Packaging, Storage & Formulations
Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.1% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Immunogen affinity purified |
Notes
Product can be stored undiluted at 4C for up to 1 month.
Alternate Names for PAC1R Antibody - BSA Free
Background
The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems. Two start codons are reported in literature, one (nt 74-76) results in a 525-amino acid protein with a signal peptide of 77 amino acids encoded by nt 74-304 and the second (nt 245-247) initiates a 468-amino acid protein with a signal peptide of 20-amino acids encoded by nt 245-304. The efficiency of these two start codons is not known. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for PAC1R Antibody (NLS948) (0)
Secondary Antibodies
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Isotype Controls
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