P2X7/P2RX7 Antibody - BSA Free

Immunohistochemistry-Frozen: P2X7/P2RX7 Antibody [NBP1-32470] - Frozen sectioned adult mouse retina. Green: P2X7 protein stained by P2X7 antibody diluted at 1:250. Red: Protein kinase C alpha staining. Blue: Fluoroshield with DAPI.

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP1-32470] - Human breast cancer, using P2X7 antibody at 1:250 dilution. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP1-32470] - Rat brain. P2X7 antibody diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

• Reactivity: Hu, Mu, Rt, Ca
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

P2X7/P2RX7 Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human P2X7/P2RX7. The exact sequence is proprietary.
• Localization: Membrane, Multi-pass membrane protein
• Predicted Species: Canine (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: P2RX7
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Frozen 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
• Theoretical MW: 69 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Bovine (86%), Guinea pig (83%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for P2X7/P2RX7 Antibody - BSA Free

• ATP receptor
• MGC20089
• P2RX7
• P2X purinoceptor 7
• P2X7
• P2X7P2X7 receptor
• P2X7R
• P2Z receptor
• purinergic receptor P2X, ligand-gated ion channel, 7
• purinergic receptor P2X7 variant A
• Purinergic receptor

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Review for P2X7/P2RX7 Antibody (NBP1-32470) (1)

Average Rating: 3

(Based on 1 review)

We have 1 review tested in 1 species: Mouse.

reviewed by: Shinya Nagasaka IHC-Fr Mouse 10/18/2017

Summary

• Application: Immunohistochemistry-Frozen
• Sample Tested: Adult kidney
• Species: Mouse
• Lot: 39974

FAQs for P2X7/P2RX7 Antibody (NBP1-32470). (Showing 1 - 1 of 1 FAQ).

1. What is the concentration of the antibody P2X7 Lot 39974?
   • The concentration of the lot 39974 is 1mg/ml.

Bioinformatics

• Gene Symbol: P2RX7