p19 INK4d Antibody

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Western Blot: p19 INK4d Antibody [NBP2-19651] - Sample (50 ug of whole cell lysate) A: Rat bone marrow, 12% SDS PAGE gel, diluted at 1:500.

Product Details

Summary
Reactivity Rt, Hu, Bv, MkSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

p19 INK4d Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human p19 INK4d. The exact sequence is proprietary.
Predicted Species
Human (100%), Monkey (98%), Bovine (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CDKN2D
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rhesus Monkey (98%), Mouse (88%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 40% Glycerol
Preservative
0.01% Thimerosal
Purity
Protein A purified

Alternate Names for p19 INK4d Antibody

  • CDK inhibitor p19INK4d
  • cell cycle inhibitor, Nur77 associating protein
  • cyclin-dependent kinase 4 inhibitor D p19
  • cyclin-dependent kinase 4 inhibitor D
  • cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
  • inhibitor of cyclin-dependent kinase 4d
  • INK4D
  • p19
  • p19-INK4D

Background

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Bioinformatics

Gene Symbol CDKN2D
Uniprot