OAS2 Antibody (HLS56/3) [PerCP]

• Reactivity: Hu
• Applications: IP, ICC/IF
• Clone: HLS56/3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PerCP

OAS2 Antibody (HLS56/3) [PerCP] Summary

• Immunogen: 2’,5’-Oligoadenylate Synthetase-2
• Specificity: Detects human OAS2.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: OAS2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for OAS2 Antibody (HLS56/3) [PerCP]

• (2-5')oligo(A) synthase 2
• (2'-5')oligo(A) synthetase 2
• (2-5')oligo(A) synthetase 2
• 2'5' oligoadenylate synthetase 2
• 2-5A synthase 2
• 2-5A synthetase 2
• 2'-5'-oligoadenylate synthase 2
• 2'-5'-oligoadenylate synthetase 2 (69-71 kD)
• 2'-5'-oligoadenylate synthetase 2, 69/71kDa
• EC 2.7.7
• EC 2.7.7.-
• MGC78578
• OAS2
• p69 OAS / p71 OAS
• p69OAS / p71OAS

Background

OAS2 encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OAS2