NSP 5 alpha 3 alpha Antibody [Alexa Fluor™ Plus 405]

Product Discontinued

NSP 5 alpha 3 alpha Antibody [Alexa Fluor™ Plus 405] Summary

• Immunogen: An internal synthetic peptide made to the human NSP 5 alpha 3 alpha protein sequence (between residues 1-100). [UniProt# Q5M775]
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SPECC1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: mouse (83%), rat (83%).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NSP 5 alpha 3 alpha Antibody [Alexa Fluor™ Plus 405]

• cytospin-B
• CYTSBcytospin B
• FLJ36955
• HCMOGT-1
• NSP
• NSP5
• Nuclear structure protein 5
• sperm antigen HCMOGT 1
• Sperm antigen HCMOGT-1
• sperm antigen with calponin homology and coiled coil domains 1
• sperm antigen with calponin homology and coiled-coil domains 1cytokinesis and spindle organization B
• sperm antigen with calponin-like and coiled coil domains 1
• structure protein NSP5a3a
• structure protein NSP5a3b
• structure protein NSP5b3a
• structure protein NSP5b3b

Background

NSP 5alpha 3alpha is a novel structure protein with potential roles in ribosome biogenesis and rRNA metabolism/processing. NSP5a3a is highly expressed in certain tumor cell lines, and may serve as a good tumor marker. In these cancer lines, NSP5a3a has been shown to interact with the nucleolar apoptosis protein B23 and may be involved in a novel p73 dependent apoptosis mechanism. Therefore, NSP5a3a is expected to become an important potential target for future cancer treatment research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPECC1