NORE1 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

NORE1 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human NORE1.

  Source: E. coli

  Amino Acid Sequence: EGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTY

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: RASSF5
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-57516.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 25 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for NORE1 Recombinant Protein Antigen

• Maxp1
• MGC10823
• MGC17344
• New ras effector 1
• NORE1A
• NORE1B
• NORE1RASSF3
• Rap1-binding protein
• RAPLnovel Ras effector 1
• Ras association (RalGDS/AF-6) domain family 5
• Ras association (RalGDS/AF-6) domain family member 5
• ras association domain-containing protein 5
• Ras effector-like protein
• regulator for cell adhesion and polarization enriched in lymphoid tissue
• Regulator for cell adhesion and polarization enriched in lymphoid tissues
• tumor suppressor RASSF3

Background

NORE1 (also referred to as Ras Association (RalGDS/AF-6) Domain Family Member 5) is a tumor suppressor and induces apoptosis. NORE1 is known to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D and HIST1H4E. NORE1 has been studied in relation to several types of cancer including lung cancer, breast cancer, clear cell renal cell carcinoma, thyroid carcinoma, and follicular thyroid carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: RASSF5