Nicotinic Acetylcholine Receptor beta Antibody

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Western Blot: Nicotinic Acetylcholine Receptor beta Antibody [NBP1-20900] - Analysis of Nicotinic Acetylcholine Receptor beta in human cerebellum lysate (35ug protein in RIPA buffer) using NBP1-20900 at 1ug/ml. Primary ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Nicotinic Acetylcholine Receptor beta Antibody Summary

Immunogen
Peptide with sequence C-QEQEDHDALKED corresponding to internal region according to NP_000738.2.
Epitope
C terminus
Predicted Species
Mouse (100%), Rat (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CHRNB1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:1000
  • Western Blot 1 - 3 ug/ml
Application Notes
WB: Approx. 55 kDa band observed in human brain (cerebellum, hippocampus, frontal cortex) lysates (calculated MW of 56.7 kDa band according to NP_000738.2).
Publications
Read Publication using NBP1-20900.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Nicotinic Acetylcholine Receptor beta Antibody

  • acetylcholine receptor subunit beta
  • ACHRB
  • ACHRBSCCMS
  • cholinergic receptor, nicotinic, beta 1 (muscle)
  • cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
  • CHRNB
  • CHRNB1
  • CMS1D
  • CMS2A
  • CMS2C
  • FLJ57107
  • nAChRB1
  • Nicotinic Acetylcholine R beta 1

Background

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Nicotinic Acetylcholine Receptor beta Antibody (NBP1-20900)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Nicotinic Acetylcholine Receptor beta Antibody (NBP1-20900). (Showing 1 - 1 of 1 FAQ).

  1. I am looking to buy antibodies against most of the nicotinic receptor subunits for WB and IHC application. Could you please indicate which of your antibodies have been used by other researchers and provide publications showing their use? Thanks.
    • A list of our antibodies directed against he nicotinic acetylcholine receptors can be found here. Any products with publications will be indicated on the search page and can be found under the publications tab on the individual product's datasheet. Furthermore, we guarantee all of our products for the applications and species list on the datasheet. This should help narrow down your search.

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Bioinformatics

Gene Symbol CHRNB1
Entrez
Uniprot