NF2/Merlin Antibody Pair

Product Discontinued

NF2/Merlin Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-NF2 (300 ul)
• Antibody pair for WB: mouse polyclonal anti-NF2 (50 ul)
• Marker: Plasma Membrane Marker
• Clonality: Polyclonal
• Gene: NF2

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NF2/Merlin Antibody Pair

• ACN
• BANF
• Merlin
• moesin-ezrin-radixin like
• Moesin-ezrin-radixin-like protein
• moesin-ezrin-radizin-like protein
• neurofibromin 2 (bilateral acoustic neuroma)
• neurofibromin 2 (merlin)
• neurofibromin-2
• NF2
• SCH
• Schwannomerlin
• Schwannomin

Background

Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility. Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: NF2