Neuromedin BR/NMBR Antibody

Images

 
Immunohistochemistry-Paraffin: Neuromedin B R/NMBR Antibody [NLS828] - Anti-NMBR antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry: Neuromedin B R/NMBR Antibody [NLS828] - Analysis of anti-NMBR antibody with brain, pituitary using this antibody at 9 ug/ ml.
Immunohistochemistry-Paraffin: Neuromedin B R/NMBR Antibody [NLS828] - Analysis of anti-NMBR antibody with human brain, glioblastoma.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Neuromedin BR/NMBR Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from C-terminus of human Neuromedin BR/NMBR.
Epitope
C-Terminus
Specificity
Human NMBR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NMBR
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 9 ug/ml
Control
Neuromedin BR/NMBR Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Monkey (89%), Marmoset (89%), Mouse (89%), Bovine (89%), Rat (84%), Canine (84%), Bat (84%), Rabbit (84%), Porcine (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Neuromedin BR/NMBR Antibody

  • Neuromedin B R
  • neuromedin B receptor
  • Neuromedin BR
  • neuromedin-B receptor
  • Neuromedin-B-preferring bombesin receptor
  • NMBR
  • NMB-R

Background

The neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NMBR
Entrez