NEDD4L Antibody Pair

Product Discontinued

NEDD4L Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: mouse monoclonal anti-NEDD4L (300 ug)
• Antibody pair for WB: mouse monoclonal anti-NEDD4L (50 ug)
• Clonality: Polyclonal
• Gene: NEDD4L
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NEDD4L Antibody Pair

• E3 ubiquitin-protein ligase NEDD4-like
• EC 6.3.2
• EC 6.3.2.-
• FLJ33870
• hNedd4-2
• KIAA0439ubiquitin-protein ligase NEDD4-like
• NEDD4.2
• NEDD4-2
• NEDL3
• neural precursor cell expressed, developmentally down-regulated 4-like
• neural precursor cell expressed, developmentally down-regulated gene 4-like
• RSP5ubiquitin-protein ligase Rsp5

Background

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: NEDD4L