NEDD4L Products

Antibodies
NEDD4L Antibody (1D2)
NEDD4L Antibody (1D2)
H00023327-M04
Species: Hu
Applications: WB, ELISA, IP
Host: Mouse Monoclonal
NEDD4L Antibody
NEDD4L Antibody
NBP1-81508
Species: Hu, Mouse, Rat
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
NEDD4L Antibody
NEDD4L Antibody
NBP1-54974
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Antibody Pairs
NEDD4L Antibody Pair
NEDD4L Antibody Pair
H00023327-PW1
Species: Hu
Applications: WB, IP
Lysates
NEDD4L Overexpression Lysate ...
NEDD4L Overexpression Lysate (Dena...
H00023327-T01
Species: Hu
Applications: WB
Proteins
NEDD4L Partial Recombinant Pr ...
NEDD4L Partial Recombinant Protein
H00023327-Q01
Species: Hu
Applications: WB, ELISA, PA
NEDD4L Recombinant Protein
NEDD4L Recombinant Protein
H00023327-P02
Species: Hu
Applications: WB, ELISA, PA
NEDD4L Recombinant Protein
NEDD4L Recombinant Protein
H00023327-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
NEDD4L RNAi
NEDD4L RNAi
H00023327-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 23327
Alternate Names
  • hNedd4-2
  • EC 6.3.2
  • E3 ubiquitin-protein ligase NEDD4-like
  • Nedd4-2
  • FLJ33870
  • NEDL3
  • NEDD4.2
  • EC 6.3.2.-
  • NEDD4-2
  • RSP5ubiquitin-protein ligase Rsp5
  • KIAA0439ubiquitin-protein ligase NEDD4-like
  • neural precursor cell expressed, developmentally down-regulated gene 4-like
  • neural precursor cell expressed, developmentally down-regulated 4-like

PTMs for NEDD4L

Learn more about PTMs related to NEDD4L.

Ubiquitination
Phosphorylation

Bioinformatics Tool for NEDD4L

Discover related pathways, diseases and genes to NEDD4L. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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