NEDD4L Products

Antibodies
NEDD4L Antibody (1D2)
NEDD4L Antibody (1D2)
H00023327-M04
Species: Hu
Applications: WB, ELISA, IP, S-ELISA
Host: Mouse Monoclonal
NEDD4L Antibody
NEDD4L Antibody
NBP1-54974
Species: Hu, Mu, Rt, Bv, Ca, Eq, Gp, Rb, Ze
Applications: WB
Host: Rabbit Polyclonal
NEDD4L Antibody (SN73-03)
NEDD4L Antibody (SN73-03)
NBP2-67678
Species: Hu, Mu, Rt
Applications: WB, IP
Host: Rabbit Monoclonal
Lysates
NEDD4L 293T Cell Transient Ov ...
NEDD4L 293T Cell Transient Overexp...
H00023327-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human NEDD4L GST ...
Recombinant Human NEDD4L GST (N-Te...
H00023327-P01
Species: Hu
Applications: WB, ELISA, Func, PA, AP
Recombinant Human NEDD4L GST ...
Recombinant Human NEDD4L GST (N-Te...
H00023327-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human NEDD4L GST ...
Recombinant Human NEDD4L GST (N-Te...
H00023327-P02
Species: Hu
Applications: WB, ELISA, PA, AP

Description

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 23327
Alternate Names
  • hNedd4-2
  • EC 6.3.2
  • E3 ubiquitin-protein ligase NEDD4-like
  • Nedd4-2
  • FLJ33870
  • NEDL3
  • NEDD4.2
  • EC 6.3.2.-
  • NEDD4-2
  • RSP5ubiquitin-protein ligase Rsp5
  • KIAA0439ubiquitin-protein ligase NEDD4-like
  • neural precursor cell expressed, developmentally down-regulated gene 4-like
  • neural precursor cell expressed, developmentally down-regulated 4-like

PTMs for NEDD4L

Learn more about PTMs related to NEDD4L.

Ubiquitination
Phosphorylation

Bioinformatics Tool for NEDD4L

Discover related pathways, diseases and genes to NEDD4L. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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