NEDD4 Antibody

Product Discontinued

NEDD4 Antibody Summary

• Immunogen: GST fusion protein corresponding to the WW2 domain (aa395-462) of rat Nedd4.
• Specificity: Recognizes rat Nedd4, Mr 115kD. Degradation products were also detected at Mr 55 and 60kD. Species cross-reactivity: mouse and human.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NEDD4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100-1:200
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris-Glycine (pH 7.4), 0.15M NaCl and 30% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for NEDD4 Antibody

• Cell proliferation-inducing gene 53 protein
• E3 ubiquitin-protein ligase NEDD4
• EC 6.3.2
• EC 6.3.2.-
• KIAA0093NEDD4-1MGC176705
• NEDD4
• NEDD-4
• Neural precursor cell expressed developmentally down-regulated protein 4
• neural precursor cell expressed, developmentally down-regulated 4
• receptor-potentiating factor 1
• RPF1

Background

Nedd4 is one of a group of mouse genes that show developmentally regulated expression in mouse embryonic brain. Nedd4 is expressed in various other embryonic tissues and persists in most adult tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NEDD4 Antibody (NBP1-40112)(1)

Publication using NBP1-40112

• Zhang X, Li B, Rezaeian AH et al. H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis. Nat Commun. 2017-03-16 [PMID: 28300060] (Human)

Bioinformatics

• Gene Symbol: NEDD4
• Entrez:
  • 4734(Human)
  • 17999(Mouse)
  • 25489(Rat)
• Uniprot:
  • Q62940(Rat)