NDFIP1 Antibody

Product Discontinued

NDFIP1 Antibody Summary

• Immunogen: Peptide with sequence C-YFDYKDESGFPKP corresponding to internal region according to NP_085048.1.
• Epitope: C-YFDYKDESGFPKP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: NDFIP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:64000
• Application Notes: WB: Preliminary experiments in human brain (frontal cortex) and mouse and rat brain lysates gave no specific signal but low background.
• Control:

  NDFIP1 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for NDFIP1 Antibody

• Breast cancer-associated protein SGA-1M
• MGC10924
• N4WBP5
• N4WBP5Putative NF-kappa-B-activating protein 164
• NDFIP1
• Nedd4 family interacting protein 1
• NEDD4 family-interacting protein 1
• NEDD4 WW domain-binding protein 5
• Putative MAPK-activating protein PM13
• Putative NFKB and MAPK-activating protein

Background

The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NDFIP1 Antibody (NB100-93471)(1)

Publication using NB100-93471

• Oliver PM, Cao X, Worthen GS et al. Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity 2006-12-01 [PMID: 17137798]

Bioinformatics

• Gene Symbol: NDFIP1
• Entrez:
  • 80762(Human)
  • 65113(Mouse)
  • 291609(Rat)
• Uniprot:
  • NP_085048.1(Human)