Natriuretic Peptide Receptor C Antibody (OTI4C3) [DyLight 650]

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF, IHC
• Clone: OTI4C3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

Natriuretic Peptide Receptor C Antibody (OTI4C3) [DyLight 650] Summary

• Immunogen: Full length recombinant protein of human Natriuretic Peptide Receptor C (NP_000899) produced in HEK293T cells.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: NPR3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Natriuretic Peptide Receptor C Antibody (OTI4C3) [DyLight 650]

• ANP-C
• ANPR-C
• ANPRCFLJ14054
• Atrial natriuretic peptide clearance receptor
• atrial natriuretic peptide receptor 3
• Atrial natriuretic peptide receptor type C
• C5orf23
• chromosome 5 open reading frame 23
• GUCY2B
• lgj
• natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptidereceptor C)
• NPR3
• NPRC
• NPR-C
• stri

Background

The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NPR3