NAPA Antibody (16D1)

Western Blot: NAPA Antibody (16D1) [NBP2-66630] - Western blot (10% SDS-PAGE) of chicken brain (lane 1), chicken kidney (lane 2), rat brain (lane 3) and rat kidney (lane 4) probed with NAPA antibody clone 16D1 at 0.2 ug/mL.

Product Discontinued

NAPA Antibody (16D1) Summary

• Immunogen: Recombinant human alpha SNAP
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: NAPA
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:5000
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5
• Preservative: No Preservative
• Purity: Affinity purified

Alternate Names for NAPA Antibody (16D1)

• alpha-SNAP
• alpha-soluble NSF attachment protein
• N-ethylmaleimide-sensitive factor attachment protein alpha
• N-ethylmaleimide-sensitive factor attachment protein, alpha
• S
• SNAPA
• SNAP-alpha

Background

38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide- sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. Alpha-SNAP (or beta-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NAPA