NAPA Products

Antibodies
NAPA Antibody
NAPA Antibody
NBP1-32493
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
NAPA Antibody
NAPA Antibody
NBP2-33593
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
NAPA Antibody
NAPA Antibody
NBP2-12752
Species: Hu, Mu, Rt, Po
Applications: WB, ELISA
Host: Rabbit Polyclonal
Lysates
NAPA Overexpression Lysate (N ...
NAPA Overexpression Lysate (Native)
NBL1-13474
Applications: WB
Proteins
NAPA Recombinant Protein Anti ...
NAPA Recombinant Protein Antigen
NBP2-33457PEP
Species: Hu
Applications: AC
NAPA Recombinant Protein Anti ...
NAPA Recombinant Protein Antigen
NBP2-33593PEP
Species: Hu
Applications: AC
NAPA Recombinant Protein
NAPA Recombinant Protein
NBP1-48365
Species: Hu
Applications: PAGE

Description

The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. Platelets contain some of the same proteins, including NSF, p115/TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types. Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 8775
Alternate Names
  • alpha-SNAP
  • S
  • SNAPA
  • N-ethylmaleimide-sensitive factor attachment protein alpha
  • SNAP-alpha
  • alpha-soluble NSF attachment protein
  • N-ethylmaleimide-sensitive factor attachment protein, alpha

Bioinformatics Tool for NAPA

Discover related pathways, diseases and genes to NAPA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.