Recombinant Human MYD118 Protein

SDS-Page: MYD118 Protein [NBC1-18436] - GADD45B, 17.8 kDa (160 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human MYD118 Protein Summary

• Description: An un-tagged recombinant protein corresponding to the amino acids 1-160 of Human MYD118
  
  

  Source: E.coli

  Amino Acid Sequence: MTLEELVACD NAAQKMQTVT AAVEELLVAA QRQDRLTVGV YESAKLMNVD PDSVVLCLLA IDEEEEDDIA LQIHFTLIQS FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW KSHGLVEVAS YCEESRGNNQ WVPYISLQER

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: GADD45B
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 17.8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 7.5)
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Human MYD118 Protein

• DKFZp566B133
• GADD45BETA
• growth arrest and DNA damage-inducible protein GADD45 beta
• growth arrest and DNA-damage-inducible, beta
• MYD118DKFZP566B133
• Myeloid differentiation primary response protein MyD118
• Negative growth regulatory protein MyD118

Background

GADD45B is a member of GADD45 family (GADD45alpha, beta, and gamma) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45B is necessary for adult neurogenesis, including brain-derived neurotrophic factor and fibroblast growth factor. And therefore, this protein is implicated in affecting synaptic plasticity. Recombinant GADD45B protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: GADD45B