Recombinant Human MUTED Protein

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SDS-Page: Recombinant Human MUTED Protein [NBP1-98901] - 15% SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

Order Details

Recombinant Human MUTED Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-187 of Human MUTED

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSGGGTE TPVGCEAAPG GGSKKRDSLG TAGSAHLIIK DLGEIHSRLL DHRPVIQGET RYFVKEFEEK RGLREMRVLE NLKNMIHETN EHTLPKCRDT MRDSLSQVLQ RLQAANDSVC RLQQREQERK KIHSDHLVAS EKQHMLQWDN FMKEQPNKRA EVDEEHRKAM ERLKEQYAEM EKDLAKFSTF

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
BLOC1S5
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 40% glycerol, 2 mM DTT, 0.1 mM PMSF, 1 mM EDTA
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human MUTED Protein

  • DKFZp686E2287
  • FLJ18427
  • MUdJ303A1.3
  • muted homolog (mouse)
  • protein Muted homolog

Background

Muted homolog, also known as MUTED, is involved in the development of lysosome related organelles, such as melanosomes and platelet dense granules. MUTED interacts with pallidin, dystrobrevin binding protein 1 and CNO/cappuccino. It is part of the biogenesis of lysosome related organelles complex 1 (BLOC1). Also, MUTED is ubiquitously expressed with higher levels in brain, bone marrow, kidney, and liver and lower levels in skeletal muscle. Recombinant human MUTED protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Additional MUTED Products

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Bioinformatics

Gene Symbol BLOC1S5