MSP/MST1 Antibody (757320) [mFluor Violet 500 SE]

• Reactivity: Mu
• Applications: IHC, B/N
• Clone: 757320
• Clonality: Monoclonal
• Host: Rat
• Conjugate: mFluor Violet 500 SE

MSP/MST1 Antibody (757320) [mFluor Violet 500 SE] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant mouse MSP/MST1
  Met1-Glu716
  Accession # P26928
• Specificity: Detects mouse MSP/MST1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) MSP alpha, rhMSP beta, rhproMSP, rhMSP, or recombinant mouse HGF is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: MST1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Neutralization
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MSP/MST1 Antibody (757320) [mFluor Violet 500 SE]

• D3F15S2
• EC 3.4.21
• hepatocyte growth factor-like protein homolog
• HGFL
• HGFLhepatocyte growth factor-like protein
• macrophage stimulating 1 (hepatocyte growth factor-like)
• Macrophage stimulatory protein
• Macrophage-stimulating protein
• MSP
• MSPDNF15S2
• MST1
• NF15S2
• SF2

Background

Mammalian STE20-like kinase 1, or MST-1, is a serine/threonine kinase that, upon cleavage, has been implicated in the promotion of chromatin condensation. MST-1 is also known as KRS2 and STK4. The C-terminus of MST-1 contains two functional NESs (nuclear export signals), which are released upon caspase-mediated cleavage. The N-terminus portion of the protein then translocates to the nucleus and will promote chromatin condensation at sufficiently high levels. Full-length MST-1 is localized to the cytoplasm.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MST1