MSP/MST1 Antibody (68801) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB, B/N
• Clone: 68801
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

MSP/MST1 Antibody (68801) [Alexa Fluor® 532] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human MSP β chain
  Val484-Gly711
  Accession # P26927
• Specificity: Detects recombinant human (rh)MSP beta chain in direct ELISAs and Western blots. Shows no cross-reactivity with rhMSP alpha chain.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Blockade of Receptor-ligand Interaction
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MSP/MST1 Antibody (68801) [Alexa Fluor® 532]

• D3F15S2
• EC 3.4.21
• hepatocyte growth factor-like protein homolog
• HGFL
• HGFLhepatocyte growth factor-like protein
• macrophage stimulating 1 (hepatocyte growth factor-like)
• Macrophage stimulatory protein
• Macrophage-stimulating protein
• MSP
• MSPDNF15S2
• MST1
• NF15S2
• SF2

Background

MSP, also known as hepatocyte growth factor-like protein (HGFl), and scatter factor-2 (SF2), is a member of the HGF family of growth factors. It is secreted as a single chain inactive precursor which is proteolytically activated to yield a biologically active disulfide-linked heterodimer of the alpha and beta chains. MSP induces keratinocyte proliferation, bone resorption, and cell migration and shape change in resident macrophages. Heterodimeric MSP binds to and activates the cell surface receptor tyrosine kinase, RON/STK, which is expressed on mature macrophages, keratinocytes, and vascular endothelium of wounded skin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.