MSK2 Antibody (261034) [Alexa Fluor® 532]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 261034
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 532

MSK2 Antibody (261034) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human MSK2
  Met1-Ser772
  Accession # O75676
• Specificity: Detects human and mouse MSK2 in Western blots. Does not detect recombinant human MSK1.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MSK2 Antibody (261034) [Alexa Fluor® 532]

• MSK2
• ribosomal protein S6 kinase, 90kDa, polypeptide 4
• RPS6KA4
• RSKB

Background

Mitogen- and stress-activated protein kinase 2 (MSK2), also known as ribosomal protein S6 kinase B (RSKB) and RPS6KA4, belongs to the family of AGC kinases. Both MSK2 and the related MSK1 have two kinase domains connected by a regulatory linker region and are activated by the mitogen-activated protein kinases ERK1, ERK2, and p38. Nuclear MSK phosphorylates and activates a number of transcription factors, including ATF1 and CREB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.