Mouse FAP DuoSet ELISA, 5 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse FAP DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: FAP

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse FAP DuoSet ELISA, 5 Plate

• 170 kDa melanoma membrane-bound gelatinase
• DKFZp686G13158
• DPPIV
• EC 3.4.21.-
• FAP
• FAPA
• Fibroblast Activation Protein alpha
• fibroblast activation protein, alpha
• Integral membrane serine protease
• Seprase
• vibronectin

Background

FAP (fibroblast activation protein-alpha; also known as seprase) is a type II transmembrane serine protease that degrades gelatin, Type I collagen, and N-terminal prolines. FAP is induced on reactive stromal fibroblasts in epithelial cancers, sarcomas, and granulation tissue, and may play roles in tumor invasion, tissue remodeling, and wound repair.

Publications for Fibroblast Activation Protein alpha/FAP (DY8647-05)(2)

Publications using DY8647-05

• Kalvala, AK;Silwal, A;Patel, B;Kasetti, A;Shetty, K;Cho, JH;Lara, G;Daugherity, B;Diesler, R;Pooladanda, V;Rueda, BR;Henske, EP;Yu, JJ;Markiewski, M;Karbowniczek, M; Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes bioRxiv : the preprint server for biology 2024-09-10 [PMID: 39314494] (Transgenic Mouse)
• Lavis, P;Pingitore, J;Doumont, G;Garabet, A;Van Simaeys, G;Lacroix, S;Passon, N;Van Heymbeek, C;De Maeseneire, C;Allard, J;Collin, A;Huaux, F;Decaestecker, C;Salmon, I;Goldman, S;Cardozo, AK;Bondue, B; Usefulness of FAP? assessment in bronchoalveolar lavage as a marker of fibrogenesis: results of a preclinical study and first report in patients with idiopathic pulmonary fibrosis Respiratory research 2023-10-25 [PMID: 37880678] (Mouse)

Review for Fibroblast Activation Protein alpha/FAP (DY8647-05) (1)

Average Rating: 5

(Based on 1 review)

reviewed by: Verified Customer 07/28/2023

Summary

• Sample Tested: mouse serum
• Lot: P338989

FAQs for Fibroblast Activation Protein alpha/FAP (DY8647-05). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: FAP