MLL5 293T Cell Transient Overexpression Lysate

Product Discontinued

MLL5 293T Cell Transient Overexpression Lysate Summary

• Description: Quality control test: Transient overexpression cell lysate was tested with Anti-MLL5 antibody by Western Blots. Plasmid: pCMV-MLL5 full-length
• Specificity: MLL5 293T Cell Transient Overexpression Lysate(Denatured)
• Gene: MLL5

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

• Type: 293T Cell Transient Overexpression
• Protein State: Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MLL5 293T Cell Transient Overexpression Lysate

• EC 2.1.1.43
• FLJ10078
• HDCMC04P
• histone-lysine N-methyltransferase MLL5
• KMT2EFLJ14026
• Lysine N-methyltransferase 2E
• MGC70452
• myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
• Myeloid/lymphoid or mixed-lineage leukemia protein 5

Background

MLL5 is a divergent member of the Drosophila Trithorax related SET and PHD domain containing chromatin regulators that are involved in the regulation of transcriptional "memory" during differentiation. Human MLL5 is located on chromosome 7q22, that is frequently deleted in myeloid leukemias. Inactivation of the Mll5 gene in mice results in a reduction in the average representation of hematopoietic stem cells, and in functional impairment of long term hematopoietic repopulation potential under competitive conditions. Overexpression of the protein also inhibits cell cycle progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: MLL5