MIG2/Kindlin-2 Antibody (3A3) [Alexa Fluor™ Plus 594]

• Reactivity: Hu, Mu, Rt, Bv, Ha
• Applications: WB, ICC/IF, IHC, IP
• Clone: 3A3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

MIG2/Kindlin-2 Antibody (3A3) [Alexa Fluor™ Plus 594] Summary

• Immunogen: Recombinant protein containing MIG2/Kindlin-2 (residues 218-486) (Uniprot: Q96AC1)
• Localization: Cytoplasm
• Specificity: Kindlin-2 (also known as Mig-2, KIND2) is an important component of cell-extracellular matrix adhesion. Kindlin-2 binds integrins and is involved in ECM adhesion, actin assembly and cell shape modulation. This monoclonal antibody recognizes kindlin-2 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FERMT2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MIG2/Kindlin-2 Antibody (3A3) [Alexa Fluor™ Plus 594]

• fermitin family homolog 2 (Drosophila)
• fermitin family homolog 2
• fermitin family member 2
• FERMT2
• KIND2
• KIND2DKFZp686G11125
• kindlin 2
• Kindlin-2
• MIG2
• mig-2
• MIG2FLJ34213
• mitogen inducible gene 2 protein
• Mitogen-inducible gene 2 protein
• PH domain-containing family C member 1
• pleckstrin homology domain containing, family C (with FERM domain) member 1
• pleckstrin homology domain containing, family C member 1
• Pleckstrin homology domain-containing family C member 1
• PLEKHC1
• PLEKHC1FLJ44462
• UNC112
• UNC112B

Background

Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FERMT2